William Francis Ludolph (January 21, 1900 – April 8, 1952), nicknamed "Wee Willie", was a professional baseball player. He was a right-handed pitcher for one season (1924) with the Detroit Tigers. For his career, he recorded no decisions with a 4.76 earned run average, and 1 strikeout in 5+2⁄3 innings pitched.
An alumnus of St. Mary's College of California, he was born in San Francisco, California and died in Oakland, California at the age of 52.