Chris Sale
| Date | Team | Opponent | Result | IP | H | R | ER | BB | SO | PA | 2B | 3B | HR | GO | FO | MISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-08-14 | BOS | vs. BAL | W, 16-2 | 5.0 | 6 | 2 | 2 | 0 | 8 | 20 | 1 | 0 | 2 | 4 | 2 | SP, W |
| 2021-08-20 | BOS | vs. TEX | W, 6-0 | 5.0 | 5 | 0 | 0 | 1 | 5 | 20 | 1 | 0 | 0 | 5 | 3 | SP, W |
| 2021-08-26 | BOS | vs. MIN | W, 12-2 | 5.1 | 2 | 2 | 2 | 2 | 8 | 21 | 0 | 0 | 1 | 3 | 5 | SP, W |
| 2021-09-01 | BOS | @ TBR | W, 3-2 | 6.0 | 6 | 2 | 2 | 2 | 3 | 25 | 0 | 0 | 1 | 7 | 4 | SP |
| 2021-09-06 | BOS | vs. TBR | L, 11-10 | 3.2 | 10 | 5 | 1 | 1 | 6 | 23 | 0 | 1 | 0 | 1 | 4 | SP |
| 2021-09-17 | BOS | vs. BAL | W, 7-1 | 5.0 | 2 | 1 | 1 | 0 | 1 | 17 | 0 | 0 | 1 | 9 | 4 | SP, W |
| 2021-09-22 | BOS | vs. NYM | W, 12-5 | 5.0 | 6 | 2 | 2 | 2 | 8 | 22 | 1 | 0 | 0 | 3 | 3 | SP, W |
| 2021-09-28 | BOS | @ BAL | L, 4-2 | 5.1 | 4 | 3 | 3 | 1 | 6 | 21 | 0 | 0 | 1 | 3 | 6 | SP, L |
| 2021-10-03 | BOS | @ WAS | W, 7-5 | 2.1 | 4 | 2 | 2 | 3 | 7 | 14 | 2 | 0 | 0 | 0 | 0 | SP |
| 2021-10-08 | BOS | @ TBR | W, 14-6 | 1.0 | 4 | 5 | 5 | 1 | 2 | 8 | 0 | 0 | 1 | 0 | 1 | SP |
| 2021-10-15 | BOS | @ HOU | L, 5-4 | 2.2 | 5 | 1 | 1 | 1 | 2 | 15 | 0 | 0 | 0 | 2 | 4 | SP |
| 2021-10-20 | BOS | vs. HOU | L, 9-1 | 5.1 | 3 | 4 | 2 | 2 | 7 | 22 | 1 | 0 | 1 | 5 | 5 | SP, L |
| Total Games: 12 | ||||||||||||||||